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Rituximab is a targeted treatment used to manage certain cancers, like specific types of lymphoma, and autoimmune diseases. Rituximab is the active ingredient available in Rituxirel brand. It is a monoclonal antibody that specifically targets B cells, which are immune cells involved in these conditions. 

By attaching to these B cells, Rituximab helps the immune system recognize and destroy them, reducing inflammation and slowing tumor growth. The medication is given through an IV drip, allowing it to enter the bloodstream gradually. This treatment usually takes place in a hospital or clinic, where healthcare professionals can keep an eye on patients for any reactions.

Uses 

Rituximab is used to treat various B-cell-related conditions, including several types of cancers and autoimmune diseases.

Cancers

Rituximab is effective for different cancers, such as:

• Non-Hodgkin’s Lymphoma: This cancer occurs when B cells grow out of control and form tumors. Rituximab attaches to these cancer cells, helping the immune system recognize and destroy them, which can slow or stop the growth of the cancer.

• Chronic Lymphocytic Leukemia (CLL): In CLL, abnormal B cells build up in the blood and bone marrow. Rituximab targets these cells, assisting the immune system in getting rid of them and improving outcomes for patients.

• Follicular Lymphoma: Rituximab is often used to treat follicular lymphoma, a type of non-Hodgkin’s lymphoma that usually grows slowly. It targets the B cells involved, helping to shrink tumors and improve patient outcomes.

Autoimmune Diseases

Rituximab is also used to treat several autoimmune diseases, including:

• Rheumatoid Arthritis: In this condition, B cells mistakenly attack the body’s own tissues, causing inflammation, pain, and joint damage. Rituximab lowers the number of B cells, which helps calm the immune system and ease symptoms.

• Systemic Lupus Erythematosus (SLE): In SLE, the immune system attacks healthy tissues, leading to widespread inflammation. Rituximab helps by reducing B cell levels, which lowers the immune system’s activity.

• Vasculitis: This condition involves inflammation of blood vessels. Rituximab can help decrease inflammation by targeting the B cells involved in the immune response.

Dosage and Treatment

The amount of Rituximab and how often you get it depends on your condition and health. It’s usually given as an infusion, which takes several hours.

• For cancers, treatment is often done in cycles. You might receive an infusion weekly for a few weeks, followed by a rest period.

• For autoimmune diseases, treatment often involves two doses spaced two weeks apart. After this, you may not need another dose for several months, depending on your progress.

Your doctor will create a treatment plan based on your specific needs. You’ll have breaks between treatments to allow your body to recover.

Common Side Effects

Rituximab, like any medication, can cause side effects. Here are some you might experience:

• Infusion reactions: Some people may feel feverish, get chills, or develop a rash during or after treatment. This is why you will be monitored while receiving the infusion.

• Increased risk of infections: Rituximab weakens the immune system, so you could be more prone to infections.

• Hepatitis B reactivation: If you previously had Hepatitis B, Rituximab can reactivate the virus. Your doctor will test you for this before starting treatment.

• Low blood cell counts: You might experience fatigue, easy bruising, or higher chances of infection because of lower blood cell counts.

• Rare brain infection (PML): In very rare cases, Rituximab can increase the risk of a serious brain infection called PML, which can be life-threatening.

• Heart problems: If you have heart conditions, be cautious. Rituximab may cause heart
  issues during or after the infusion.
   

Precautions

Before beginning treatment with Rituximab, consider the following precautions:

• Share your complete medical history with your doctor, especially if you have a history of infections like Hepatitis B or C, heart problems, or lung issues.

• Provide a list of all the medications and supplements you are currently taking, as some can interact with Rituximab.

• Avoid live vaccines during treatment and for a while afterward; talk with your doctor about which vaccines are right for you.

• Let your doctor know about any allergies, especially to medications, since some people may react to Rituximab.

• Stay at the treatment center for monitoring during and after your first infusion to catch any immediate reactions.

• Take steps to reduce your risk of infections by practicing good hygiene and avoiding crowded places.

• Discuss any dietary concerns with your doctor, as certain foods might affect your immune system.

Alongside all that, consider bringing a friend or family member to your appointments for support and to help with questions.

Price & Availability

Rituximab is costly because it’s complex to produce and requires careful handling when given to patients. Although it’s available in many countries, the price can be a big challenge. 

For instance, the Rituximab price in the Philippines is quite high, and the Rituximab price in Malaysia is similarly steep, ranging from $7,000 to $11,000 based on dosage. These costs are mainly due to production expenses and differences in healthcare systems. Rituximab price in India are much lower than other countries like USA, UK, UAE, Philippines, Malaysia etc.

However, we provide Rituximab worldwide at more affordable prices, making it easier to access in these areas. For the current lowest price info please send us your enquiry now.

Rituximab Safety Advice

Alcohol

Rituximab doesn’t directly interact with alcohol, but it’s wise to limit drinking. Alcohol can harm the liver, which is important to protect while on this drug. Since Rituximab also stresses the liver, combining them might increase liver problems. Always discuss your drinking habits with your doctor.

Pregnancy

Rituximab use in pregnancy has been studied in a small number of women. There is no strong evidence that it harms the baby’s development, but more research is needed. Using rituximab late in pregnancy may affect the baby’s immune system. Live vaccines should be avoided for several months after birth. A doctor can guide you on vaccination timing.

Breastfeeding

Rituximab levels in breast milk are low, and most infants show no problems. It is advised to stop breastfeeding during treatment and for 6 months after the last dose. Waiting 2 weeks after giving birth before resuming therapy can help reduce transfer to the baby.

Driving

Rituximab usually doesn’t affect driving ability, but it can cause dizziness or fatigue after treatment. If you feel unwell following an infusion, avoid driving or using heavy machinery. Your safety is important, so pay attention to how your body feels before getting behind the wheel.

Liver

If you have liver issues or a history of Hepatitis B, let your doctor know before starting Rituximab. This medication can strongly affect liver function, so regular blood tests are needed. Keeping track of your liver health is important to catch any problems early while on treatment.

Doctor Advice

Doctors often advise patients using Rituximab to have regular blood tests to monitor immune function and liver health. They may suggest reporting any signs of infection, such as fever or fatigue. Staying well-hydrated and resting after infusions is also important for managing side effects effectively.