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What is Gefitinib 250 mg Tablet?

Iressa 250 mg is a cancer chemotherapy drug. Gefitinib interferes with the growth of cancer cells and slows their growth and spread in the body.

The drug is used in the treatment of non-small cell lung cancer. Gefitinib tablets contain 250mg of Iressa and are available as brown film-coated tablets for daily oral administration.

How dangerous is non-small cell lung cancer?

Lung cancer is currently considered the most dangerous disease with high morbidity and high mortality rates. Non-small cell cancer is a common form of lung cancer.

These cancer cells grow silently in the lung cysts, lung tissue. The symptoms of the disease are also not obvious, so the patient does not know they have cancer. When detected, cancer cells have overgrown and metastasized to other cells or parts of the body.

Non-small cell cancer accounts for 85% of lung cancer patients, causing high mortality. Therefore, timely detection is necessary for effective and safe treatment.

What are the uses of Gefitinib 250mg Tablet?

Medicines used to treat lung cancer work by slowing or stopping the growth of cancer cells. Drugs that block a certain protein (an enzyme called tyrosine kinase).

How is Gefitinib treated for non-small cell lung cancer?

Currently, there are many effective treatments for non-small cell lung cancer. And the drug Gefitinib is used by oncologists as the best cancer cell inhibitor therapy today

What is the mechanism of treatment for lung cancer of Gefitinib 250mg?

The composition of the drug Gefitinib contains 250 mg of Iressa which is an active anti-cancer agent. Mechanism of chemotherapy tyrosine kinase inhibitors, to inhibit the growth of cancer cells, growth and metastasis to other parts of the body

The chemical Iressa combines on the cell surface, inactivating the cancer cell's protein, making the cells unable to grow.

How does Gefitinib treat non-small cell cancer?

Gefitinib 250mg medicine is used to treat non-small cell lung cancer in the lungs or has spread to other parts of the body. Lung cancer when chemotherapy was performed but failed.

Or treatment for non-small cell lung cancer that is growing in the lung or has spread. Have had platinum-based or taxan-based chemotherapy.

What are the side effects of Gefitinib 250mg?

1. Most people do not experience all of the side effects listed;
2. Side effects are usually predictable in terms of onset and duration;
3. Side effects are almost always reversible and will go away after treatment is completed;
4. There are many options to help minimize or prevent side effects;

There is no relationship between the presence or severity of side effects and the effectiveness of the drug.

1. Common side effects of Gefitinib occur more than 30%
Diarrhea
Skin reactions (rash, acne)

2. Less common Gefitinib 250mg side effects occur in about 10-29%
Nausea, itching
Poor eating, eye irritation
The drug has a strong inhibitory effect on cells, but also causes many side effects on the user's body.

3. Rare side effects of Gefitinib about 1%
Serious side effect of interstitial lung disease (pneumonia, or pneumonia without infection).
When this side effect occurs, it is often accompanied by difficulty breathing with a cough or a low-grade fever that requires hospitalization. 1/3 of cases resulted in death.
If sudden shortness of breath, cough, and/or fever occurs while taking Iressa, notify your healthcare professional.

4. Note about drug side effects
The drug has an effect on the eyes, blurred vision, eye pain, decreased vision
Some patients will experience chest pain when using the drug
Side effects such as jaundice, bloody stools, unexplained bleeding, prolonged body fatigue.
Drugs that affect the digestive system: causing indigestion, vomiting, constipation, flatulence, loss of appetite... If the condition occurs for a long time, you should immediately notify the doctor for a suitable dose change. well suited.
Not all side effects are listed above. Some rare cases (occurring in less than 10% of patients) are not listed here.

What drugs interact with Gefitinib 250mg?

Your doctor or pharmacist may already be aware of any possibledrug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

1. Blood thinners (warfarin);
2. Medicines that reduce stomach acid (eg, ranitidine, cimetidine, famotidine, omeprazole, lansoprazole, rabeprazole);
3. certain liver enzyme inhibitors (CYP 3A4 inhibitors such as ketoconazole, itraconazole, erythromycin,
4. clarithromycin), vinorelbine, NSAIDs (such as ibuprofen, naproxen), corticosteroids (such as prednisone);
5. Some drugs that induce liver enzymes such as rifamycin (eg, rifampin, rifabutin), St. John's wort or phenytoin will stimulate certain liver enzymes (CYP 3A4).
6. Your dose of Iressa may need to be increased if you are using these medicines. Consult your doctor or pharmacist for more details.

Gefitinib 250 mg Tablet dose

Gefitinib drug with high medicinal ingredients, strong effects on the body. Therefore, the use of the drug requires a doctor's prescription.

How to use Gefitinib?

The recommended dose of Gefitinib 250 mg 1 tablet/day is equivalent to 250mg/day. Drink before or after meals. Cycle time to ensure a stable dose of drug absorbed into the body.

Using the liquid form, drop the compressed tablet into the non-carbonated water and stir until completely dissolved. Do not crush the medicine

What drug does Gefitinib recommend for each patient?

The drug is not recommended for use in children and adolescents under 18 years of age.

1. Gefitinib 250mg drug does not adjust the dose for patients of different ages, genders and weights without a doctor's prescription.
2. For patients with intolerance to the drug, it is necessary to control and stop using the drug, then use it again with a dosage of 250 mg as prescribed by the doctor.
3. Do not use in patients who are allergic to any of the ingredients
4. Contraindicated for use in pregnant and lactating women

How should Gefitinib 250mg be stored ?

1. Store at room temperature between 68 and 77 degrees F (20-25 degrees C) away from light and moisture.
2. Do not store in the bathroom. Keep all medications away from children and pets.
3. Do not flush Gefitinib down the toilet or pour it down the drain unless instructed to do so.
4. Properly dispose of this product when it is expired or no longer needed.

What are some self-care tips for Gefitinib while on medication?

1. Drink at least two to three liters of fluid every 24 hours, unless you are instructed otherwise.
2. This medicine causes little nausea. But if you have nausea, take an anti-nausea medication as prescribed by your doctor and eat small, frequent meals. Sucking on lozenges and gum can also help.
3. Avoid sun exposure. Wear SPF 15 (or higher) sunscreen and protective clothing.
4. In general, drinking alcohol should be kept to a minimum or completely avoided, which you should discuss with your doctor.
5. You should rest a lot. and maintain good nutrition.

If you experience symptoms or side effects, be sure to discuss them with your healthcare team. They can prescribe medications and/or make other recommendations that are effective in managing such problems.

What should Gefitinib do in case of an overdose?

Symptoms of a Gefitinib overdose (Iressa or Iressa) tend to be similar to side effects caused by the drug, although often more severe.

Seek emergency medical attention for immediate treatment.